ASYMMETRIC WOLBACHIA SEGREGATION DURING EARLY BRUGIA MALAYI EMBRYOGENESIS DETERMINES ITS DISTRIBUTION IN ADULT HOST TISSUES.

Asymmetric Wolbachia segregation during early Brugia malayi embryogenesis determines its distribution in adult host tissues.

Wolbachia are required for filarial nematode survival and fertility and contribute to the immune responses associated with human filarial diseases.Here we developed whole-mount immunofluorescence techniques to characterize Wolbachia somatic and germline transmission patterns and tissue distribution in Brugia malayi, a nematode responsible for lymph

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